Hydrogel-based Drug Delivery System Market (By Polymer Origin: Natural, Synthetic, Hybrid; By Delivery Route: Subcutaneous, Ocular, Oral Cavity, Topical, Other) - Global Industry Analysis, Size, Share, Growth, Trends, Revenue, Regional Outlook 2021 – 2030

Category: Healthcare, Pharmaceuticals & Medical Devices

Publisher: Trends Market Research

Status: On-going

The global Hydrogel-based Drug Delivery System market size is expected to be worth around US$ 20.6billion by 2030, according to a new report by Trends Market Research.

The global Hydrogel-based Drug Delivery System market size was valued at US$ 15.9 billion in 2020 and is anticipated to grow at a CAGR of 17.5% during forecast period 2021 to 2030.

Growth Factors

Hydrogel-based drug delivery systems deliver the therapeutic drug directly at the target site and in a sustained manner. This can leverage beneficial outcomes such as improved efficacy, reduced side effects, and decreased dosage for patients and formulators. Hydrogel-based drug delivery systems are appealing and have been used in many branches of medicine such as oncology, pain management, immunology, cardiology, and wound management.

The unique physical properties of hydrogel attract their interest in use for drug delivery applications. The porosity and drug loading capacity of hydrogels can be adjusted by modifying the density of cross-linking. This helps them to protect liable large drug molecules from degradation increasing the half-life. Many research studies have been carried out to examining the delivery of insulin orally using hydrogel systems. As patient compliance issues are frequently reported with injectable insulins such innovation is expected to be a disruptive technology in the diabetes care market.

Report Highlights

 The natural segment dominated the market for hydrogel-based drug delivery systems and accounted for the largest revenue share of 42.3% in 2020. Based on polymer origin the hydrogel can be classified into three main types natural, synthetic and hybrid. Proteins such as gelatin, lysosome, and collagen; and polysaccharides such as chitosan, hyaluronic acid, and alginate are used in the manufacturing of natural hydrogels. They have good cell adhesion properties but due to their mechanical and stability issues recently are less preferred in formulating drug delivery systems.

Hydrogel-based drug delivery systems are made of synthetic polymer and are gaining more acceptance than naturally derived polymer owing to their higher drug absorbing capacity, improved mechanical properties, enhanced lifetime, and controllable degradation features. Poly (vinyl pyrrolidone) starch, Poly (vinyl pyrrolidone), and Poly (acrylic acid) are the widely used synthetic polymer in drug delivery applications.

The ocular segment dominated the market for hydrogel-based drug delivery systems and accounted for the largest revenue share of 48.5% in 2020. Hydrogels are commonly used in ocular drug delivery applications because most of the hard and contact lenses are made of hydrogel films. So, it becomes easy to incorporate therapeutic drugs into contact lenses. Dextenza and Lacriset are hydrogel-based ocular drug delivery systems approved for clinical use. Additionally, there are numerous ongoing clinical trials specific to hydrogel contact lens-based drug delivery systems, which, in turn, is fueling the market growth. For instance, Massachusetts Eye and Ear Infirmary are conducting a clinical trial to study the delivery of dexamethasone drug through the hydrogel contact lens.

The subcutaneous drug delivery segment is expected to witness a CAGR of 10.3% in the market for hydrogel-based drug delivery systems over the forecast period. Hydrogel being biodegradable material they are extensively used in the formulation of subcutaneous drug delivery systems. The implants degrade naturally inside the body thereby the need for its surgical removal is eliminated.

 North America dominated the hydrogel-based drug delivery systems market and accounted for the largest revenue share of 56.1% in 2020. The presence of efficient reimbursement that covers the cost of modern therapies, the domicile presence of hydrogel suppliers, and frequent product launches are the key factors expected to contribute to market growth in the region. 

Key Players


  • Blairex Laboratories, Inc.

  • Johnson & Johnson

  • Bausch and Lomb

  • Medtronic

  • Ocular Therapeutix, Inc.

  • Ferring B.V.

  • Endo International plc

  • Akorn, Incorporated

  • Tolmar Pharmaceuticals, Inc.

Market Segmentation

  • Polymer Origin Outlook 

    • Natural

    • Synthetic

    • Hybrid

  • Delivery Route Outlook 

    • Subcutaneous

    • Ocular

    • Oral Cavity

    • Topical

    • Other

  • Regional Outlook

    • North America

      • U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

      • France

      • Italy

      • Spain

    • Asia Pacific

      • China

      • Japan

      • India

      • Thailand

      • South Korea

    • Latin America

      • Brazil

      • Mexico

      • Argentina

    • Middle East & Africa

      • South Africa

      • Saudi Arabia

      • UAE

The Hydrogel-based Drug Delivery System market research report covers definition, classification, product classification, product application, development trend, product technology, competitive landscape, industrial chain structure, industry overview, national policy and planning analysis of the industry, the latest dynamic analysis, etc., and also includes major. The study includes drivers and restraints of the global market. It covers the impact of these drivers and restraints on the demand during the forecast period. The report also highlights opportunities in the market at the global level.

The report provides size (in terms of volume and value) of Hydrogel-based Drug Delivery System market for the base year 2020 and the forecast between 2021 and 2030. Market numbers have been estimated based on form and application. Market size and forecast for each application segment have been provided for the global and regional market.

This report focuses on the global Hydrogel-based Drug Delivery System market status, future forecast, growth opportunity, key market and key players. The study objectives are to present the Hydrogel-based Drug Delivery System market development in United States, Europe and China.

It is pertinent to consider that in a volatile global economy, we haven’t just conducted Hydrogel-based Drug Delivery System market forecasts in terms of CAGR, but also studied the market based on key parameters, including Year-on-Year (Y-o-Y) growth, to comprehend the certainty of the market and to find and present the lucrative opportunities in market.

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